Clsi M22a3 Pdf New! -
Quality Control for Commercially Prepared Microbiological Culture Media
It applies to all commercial media regardless of packaging, such as plates, tubes, or bottles. Major Updates in the Third Edition (A3)
The full document is available in electronic PDF format from various official standards retailers. Go to product viewer dialog for this item. CLSI M22-A3 (R2018) clsi m22a3 pdf
While certain media are exempt from full retesting, labs must still perform a for physical defects upon receipt of every shipment. The standard requires monitoring for:
The acceptable failure rate cutoff for exempting media was increased from 0.3% to 0.5% . CLSI M22-A3 (R2018) While certain media are exempt
Excessive moisture, dehydration, or frozen/melted agar. Contamination: Any visible growth or excessive bubbles. Purchasing and Access
M22-A3 introduced several significant changes from the previous M22-A2 version based on extensive surveys by the : Contamination: Any visible growth or excessive bubbles
Focus on visual inspection and documentation of media upon receipt rather than full organism-based retesting for "exempt" media.
Includes new recommendations for QC of media used to recover difficult-to-grow pathogens. Laboratory Inspection Requirements
It explicitly defines the roles of the manufacturer, distributor, and end-user laboratory.