ASIO-compatible drivers are essential for low latency.
The short answer is , but with caveats. Cubase 5 was originally designed for Windows XP and Windows 7. While Windows 10 features excellent backward compatibility, you may encounter issues with the installer, administrative permissions, or older 32-bit plugins. Key Technical Requirements OS: Windows 10 (64-bit version). RAM: Minimum 4GB (8GB recommended for modern VSTs). cubase 5 windows 10 64 bit download verified
Cubase 5 on Windows 10 (64-bit): How to Install and Optimize ASIO-compatible drivers are essential for low latency