When prompted for Video configuration, select ePSXe GPU Core 2.0.0 from the dropdown menu. Best Configuration for High Graphics

To get the most out of the GPU Core 2.0.0, use the following recommended settings in the menu: Recommended Value Description Internal Resolution x4 (Slowest) Provides the highest level of clarity for 3D games. Stretching Mode Stretch to fill Useful for modern screens, though 4:3 is more "authentic". Shaders Lottes or Hyllian Adds a CRT-like scanline effect for a nostalgic feel. GTE Accuracy Enabled Significantly reduces the polygon wobble seen in 3D titles. Troubleshooting & Compatibility ePSXe Plugin Guide (Windows) - NGEmu

Launch epsxe.exe . If it's your first time, the configuration wizard will appear.

Unlike older software plugins that struggled with high resolutions, the GPU Core 2.0.0 leverages and GLSL shaders to drastically improve graphics while maintaining performance.