This is the most common error. You need to install the Microsoft Visual C++ 2010 Redistributable (both x86 and x64 versions) from the official Microsoft site.
Click and select the folder where your Silkroad client is installed. mbot vsro110exe
Check your "Inventory" and "Filter" tabs. Ensure you have clicked "Search" to load the item list and set "Pick" to "Yes" for the items you want. This is the most common error